5-HT modulation of pain perception in humans
نویسندگان
چکیده
منابع مشابه
Transcutaneous electrical nerve stimulation and conditioned pain modulation influence the perception of pain in humans.
BACKGROUND Research in animal models suggests that transcutaneous electrical nerve stimulation (TENS) and conditioned pain modulation (CPM) produce analgesia via two different supraspinal pathways. No known studies have examined whether TENS and CPM applied simultaneously in human subjects will enhance the analgesic effect of either treatment alone. The purpose of the current study was to inves...
متن کاملImaging CNS modulation of pain in humans.
Pain is a highly complex and subjective experience that is not linearly related to the nociceptive input. What is clear from anecdotal reports over the centuries and more recently from animal and human experimentation is that nociceptive information processing and consequent pain perception is subject to significant pro- and anti-nociceptive modulations. These modulations can be initiated refle...
متن کاملThe Perception and Endogenous Modulation of Pain
Pain is often perceived an unpleasant experience that includes sensory and emotional/motivational responses. Accordingly, pain serves as a powerful teaching signal enabling an organism to avoid injury, and is critical to survival. However, maladaptive pain, such as neuropathic or idiopathic pain, serves no survival function. Genomic studies of individuals with congenital insensitivity to pain o...
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ژورنال
عنوان ژورنال: Psychopharmacology
سال: 2017
ISSN: 0033-3158,1432-2072
DOI: 10.1007/s00213-017-4686-6